Certified Lactation Consultant Practice Exam 2026 - Free Lactation Consultant Practice Questions and Study Guide

Lactogenesis 1 refers to the first stage of milk production, which typically begins around the midpoint of pregnancy and continues until the mother gives birth. This phase involves the biochemical preparation of the breasts for milk production.

The correct answer highlights the pivotal role that a drop in progesterone levels plays during this process. As soon as the placenta is delivered, there is a significant decrease in progesterone, a hormone that has been high during pregnancy. This drop is crucial because progesterone is known to inhibit lactation. Once the levels of this hormone decline, lactogenics (like prolactin) can start to drive the breast's ability to synthesize and prepare milk.

While prolactin, produced in higher amounts following the birth and during breastfeeding, is also critical for stimulating milk production, it is the hormonal changes associated with childbirth—particularly the reduction in progesterone—that truly initiates lactogenesis 1. This allows the mammary glands to begin producing colostrum, which is a nutrient-rich fluid that precedes the production of mature breast milk.

The other choices, while related to lactation processes, do not specifically address the initiation of lactogenesis 1. Prolactin production occurs, but it is the withdrawal of progesterone